The Applied Biosystems™ 3500 Series Genetic Analyzers are specifically designed to support the demanding performance needs of validated and regulated environments while retaining the unsurpassed application versatility that life science researchers expect. The 8-capillary 3500 Genetic Analyzers continue to set the standard in capillary electrophoresis.

The Applied Biosystems™ QuantStudio™ Absolute Q™ Digital PCR System combines the power of absolute quantification via digital PCR with the simplicity of a qPCR workflow. With a single hands-on step that takes 5 minutes to complete, digital PCR is now easier than ever. The QuantStudio Absolute Q system provides a high-quality, consistent, and easy-to-use solution for researchers who want to join the quantification revolution.

EmbryoMap for labs assessing preimplantation embryo biopsy samples

Through evolution and innovation, the EmbryoMap solution has been analytically validated for detection of whole- and sub-chromosomal imbalances with highly reproducible copy-number, using cell line reference material and embryo biopsy samples

Samples are prepared for sequencing using the EmbryoMap Sample Prep Kit, sequenced on the Illumina MiSeq Sequencing System and data analysis and reporting performed using eMap software

Disclaimer: This product is labelled for Research Use Only – Not for use in diagnostic procedures.

The Applied Biosystems SeqStudio Genetic Analyzer for HID is a low-throughput, easy-to-use, convenient benchtop system that delivers gold-standard fragment analysis or Sanger sequencing with just a simple click. It is validated across a broad range of HID forensic kits to deliver answers you can trust. The SeqStudio Genetic Analyzer couples the latest advancements in touchscreen usability with the same data quality, reliability, and support you have come to expect from Applied Biosystems instruments.

Package Components

The 24-capillary 3500xL Genetic Analyzer sets the standard in capillary electrophoresis. The 3500-series instruments are the first genetic analyzers designed with a specific feature set and workflow for the Human Identification application. The complete product combines the instrument with Applied Biosystems™ reagents, consumables and software, as well as industry leading support, to provide an integrated HID system solution that significantly improves ease-of-use and application efficiencies.

• Increased Consistency – Reduced signal variation with factory standardization and optional in-lane normalization
• Real-Time Data Quality Assessment – On instrument data evaluation features provide rapid identification and re-injection of samples requiring additional processing
• Improved Thermal Control – Smaller oven design and improved door seal for more consistent data migration
• HID Specific Workflow – Pre-configured for Applied Biosystems™ amplification kits to simplify run setup and software navigation
• Effortless Consumable Installation – Convenient one-time use consumable packaging
• Consumable Tracking with RFID Technology – On-instrument, real-time monitoring of consumable consumption and expiration
• Enhanced Throughput – Faster data generation with 8 or 24 capillary arrays and shorter run times
• Improved Polymer Pump Design – Reduced waste and fewer bubbles for better data quality
• Simplified Instrument Installation & Operation – New solid-state laser eliminates need for high voltage wiring and external venting
• Streamlined Instrument Maintenance – HID specific performance check and maintenance scheduling tools
• Data Chain of Custody – Controlled access and tracking through Security, Audit and eSig features

The 3500 analyzer is shipped with the following system components:

• Capillary Electrophoresis instrument.
• 3500 (8-capillary) array and POP™ polymer
• Human identification reagents and other consumables for system qualification.
• Dell™ computer workstation with flat-screen monitor.
• Integrated software for instrument control, data collection, quality control, and basecalling or sizing of samples.

• Consolidated Workflow: DNA denaturation and bisulfite conversion process in one step.
• High Yield: Desulfonation and purification on a spin-column allows elution of bisulfite-converted DNA in as little as 10 µl.
• Suitable for Various Downstream Applications: Bisulfite-converted DNA can be robustly PCR amplified for downstream analyses including endonuclease digestion, sequencing, microarrays, etc.