Model: iScan
Manufacturer: Illumina / USA
Fully automated Micro-array System
– The iScan status indicator lights and scan bar on the front panel show the current status of the iScan: Power (blue) – Instrument is on; Ready (green check) – Instrument has been initialized and is ready to scan; Warning (amber triangle) – Instrument error has occurred
– The scanning system uses high-performance lasers, optics, and fully automated detection systems to provide extremely rapid scan times without sacrificing data quality, which helps to process complex data when running multiple samples
– With a high signal-to-noise ratio, high sensitivity, a low limit of detection, and a broad dynamic range, the iScan System can detect single copy number changes in gene expression and DNA methylation analysis
– The system uses microarray technology, the process of scanning and analyzing are carried out on the Beadchips.
– Beadchip is based on silicon particles with the size of 1-2 μm arranged in wells with a spacing of 5.7 μm between beads, each bead is covered by hundreds to thousands copies of specific oligonucleotides to generate a perfect hybridization environment in terms of large area, ensuring the highest hybridization yield.
– Ability to analyze high-quality data with high call rates (>99.9%), reducing the positive false and negative false.
– Normal Scan Function: manual loading
– Automatic Scan function: Automatic sample loading with robot
– Automatic Sample Running:
– The Beadchip tray allows to analyze four Beadchips simultaneously
– The system operates simultaneously ≥24 samples per run on a Beadchip
– Number of samples / run varies by chemical reagent kits and applications
– Scan time for each sample varies by specialized kits and applications