Search
Search
Genetic testing for BRCA ½ mutations for detecting breast and ovarian cancer
BRCAaccuTest™ & BRCAaccuTest™PLUS is a regent for producing libraries for
analyzing the BRCA ½ genes using the NGS (next-generation sequencing) method,
which analyzes genomic DNA derived from blood or FFPE tissues.
BRCAaccuTest™ and BRCAaccuTest™ PLUS are a reagent kit for producing libraries for analyzing the BRCA1 and BRCA2 genes using the next generation sequencing (NGS) method, which analyzes genomic DNA derived from blood or FFPE tissue.
| BRCAaccuTest™ PLUS | ||
|---|---|---|
| Certification | CE-IVD | |
| Target disease | Breast/Ovarian cancer HBOC (Hereditary breast and ovarian cancer syndrome) |
|
| Target Enrichment method | Amplicon based method | |
| Quantity | 12 (6+6) test (1 test each for control DNA) |
24 test (1 test for control DNA) |
| Specimen | Blood, FFPE tissue, Tissue biopsy | |
| In-put DNA quantity | 10-30 ng | |
| Target gene | BRCA1 / BRCA2 | |
| Target region | 22.4 kb (all protein coding region, splicing regions, selected promoter, UTR, intron regions) | |
| amplicon | 160 (2 pools) | |
| Hands on time | >5 hrs | |
| Variants type | SNV, In, Del, Dup, CNV* | |
| NGS platform & reagent kit | illumina MiSeq, MiSeq Dx / MiSeq Reagent Nano, Micro kit, v2, 300cycles | |
| Samples throughput | Germline (11) / Somatic (5) | Germline (23) |
| Analysis solution | NGeneAnalySys™ (CE) | |
*CNV: RUO, Research Use Only
Supplier
NgeneBio
The EntroGen NGS Targeted Hotspot Panel is a comprehensive assay that detects clinically relevant mutations in solid tumors using next-generation sequencing, compatible with fresh frozen and FFPE samples. It offers high sensitivity, low DNA input, and the ability to batch up to 12 samples in a single run, making it ideal for labs with limited sample volumes.
BRCAaccuTest™ PLUS with CE-IVD certificate for HBOC Breast/Ovarian Cancer Test
Model: NovaSeq 6000
Manufacturer: Illumina/USA
– Scalable platform
Match data output, time to results, and price per sample to study needs
– Flexible performance
Configure sequencing method, flow cell type, and read length to support a broad range of applications
– Streamlined operation
Increase lab efficiency with a simplified workflow and reduced hands-on time
The NextSeq 2000 Sequencing System uses patterned flow cells similar to those that power the NovaSeq™ 6000 System. The result is a highly flexible and scalable benchtop system that offers the highest cluster density flow cell of any on-market NGS system to date, driving down the cost per gigabase (Gb) of the sequencing run.
Model: NextSeq 1000
Manufacturer: Illumina
Origin: Singapore/United States
Launching year: 01/2020
The PANA RealTyper™ HPV Screening Kit is a CE marked diagnostic device in accordance with the European Union in vitro Diagnostic Medical Device Directive 98/79/EC
PANA RealTyperTM HPV Kit is a CE marked diagnostic device in accordance with the European Union in vitro Diagnostic Medical Device Directive 98/79/EC.
Model: NovaSeq 6000
Manufacturer: Illumina/USA
– Scalable platform
Match data output, time to results, and price per sample to study needs
– Flexible performance
Configure sequencing method, flow cell type, and read length to support a broad range of applications
– Streamlined operation
Increase lab efficiency with a simplified workflow and reduced hands-on time
TruSight Tumor 26 Kit includes library preparation reagent set and uses next-generation sequencing (NGS) technology to provide a comprehensive assessment of 26 genes that are commonly related to mutations in solid tumors and somatic variants
Developed with cancer genomics experts in collaboration, oligos ready-to-use, pre-engineered oligos allow researchers to sequence a wide range of genes and single nucleotide polymorphisms (SNPs) in advance. this is related to cancer predisposition
Assisted Reproductive 
Prenatal screening 
New-born screening 
Screening 
Diagnosis 
Early detection 
Monitoring 
Illumina infectious diseases testing group 
GeneProof infectious diseases testing group 
Panagene infectious diseases testing group 
Digital forensics 
Inspection of Ballistics and Mechanical Traces 
Document examination 
Crime scene examination 
