Genetic testing to find BRCA 1/2 mutation for detecting breast and ovarian cancer


NGenebio
Reagents
Detecting breast and ovarian cancer
BRCAaccuTest™ PLUS with CE-IVD certificate for HBOC Breast/Ovarian Cancer Test
Genetic testing to find BRCA 1/2 mutation for detecting breast and ovarian cancer
| BRCAaccuTest™ PLUS | ||
|---|---|---|
| Certification | CE-IVD | |
| Target Gene | Breast Cancer/Ovarian cancer HBOC (Hereditary breast and ovarian cancer syndrome) |
|
| Treatment-enhancing methods | Method of Amplicon | |
| Numbers | 12 (6+6) tests (1 tests for DNA control) |
24 tests (1 tests for DNA control) |
| Samples | Blood, FFPE, biopsy tissue | |
| Amount of DNA input | 10-30 ng | |
| Target Gene | BRCA1 / BRCA2 | |
| Target Area | 22.4 kb (all protein coding zones, joins, startup zones selected, UTR, intron regions) | |
| amplicon | 160 (2 pools) | |
| Timing | >5 hrs | |
| Variant | SNV, In, Del, Dup, CNV* | |
| NGS platform & reagent | illumina MiSeq, MiSeq Dx / MiSeq Reagent Nano, Micro kit, v2, 300cycles | |
| Throughput Sample | Germline (11) / Somatic (5) | Germline (23) |
| Analysis Solution | NGeneAnalySys™ (CE) | |
*CNV: Only ROU
Supplier
Ngenebio


EntroGen’s BRCA Complete™ Expanded Panel is a comprehensive NGS solution that detects both germline and somatic mutations in genes like BRCA1, BRCA2, CHEK2, PALB2, RAD51C, and TP53 with high sensitivity and specificity. Compatible with blood, fresh frozen, and FFPE samples, the panel reduces allele dropouts and off-target reads using a tiled amplicon PCR approach. It includes reagents for library preparation and user-friendly software for easy mutation identification, along with quality control assays to ensure high-quality data without repeat sequencing.


SOLIDaccuTest™ is an excellent tool for discovering variants associated with solid tumors using a comprehensive approach to next-generation sequencing (NGS). It reflects the latest research trends and is optimized for medical purposes by selecting essential genes of solid tumors including lung, colon, breast, skin brain, stomach and ovarian cancers, etc.


Model: NextSeq 1000
Manufacturer: Illumina
Origin: Singapore/United States
Launching year: 01/2020


The PANA RealTyper™ HPV Screening Kit is a CE marked diagnostic device in accordance with the European Union in vitro Diagnostic Medical Device Directive 98/79/EC


PANA RealTyperTM HPV Kit is a CE marked diagnostic device in accordance with the European Union in vitro Diagnostic Medical Device Directive 98/79/EC.


DxFLEX is a new clinical flow cytometry platform derived from the successful CytoFLEX. The advanced sensitivity and intuitive software DxFLEX makes flow cytometry routine for both novice and expert flow cytometry technicians and promotes standardization. Functionality in the autoloader facilitates accurate results and sample tracking.


Model: NovaSeq 6000
Manufacturer: Illumina/USA
– Scalable platform
Match data output, time to results, and price per sample to study needs
– Flexible performance
Configure sequencing method, flow cell type, and read length to support a broad range of applications
– Streamlined operation
Increase lab efficiency with a simplified workflow and reduced hands-on time


TruSight Tumor 26 Kit includes library preparation reagent set and uses next-generation sequencing (NGS) technology to provide a comprehensive assessment of 26 genes that are commonly related to mutations in solid tumors and somatic variants


Model: Nextseq 550
Manufacturer: Illumina/USA
– Is the only sequencing system capable of deploying applications running sequencing and reading microarray biochips
– New generation DNA sequencing system using synthetic sequencing technology: Sequencing by Synthesis – SBS
– The whole process of gene sequencing is conducted on the surface of flow cells, convenient to use and easy to manipulate.


Model: MiSeq
Manufacturer: Illumina/USA
– The MiSeq System combines cluster generation, amplification, sequencing and data analysis on a single system
– The system is most widely used, with next-generation sequencing technology – Sequencing by Synthesis – SBS