Genetic testing to find BRCA 1/2 mutation for detecting breast and ovarian cancer


NGenebio
Reagents
Detecting breast and ovarian cancer
BRCAaccuTest™ PLUS with CE-IVD certificate for HBOC Breast/Ovarian Cancer Test
Genetic testing to find BRCA 1/2 mutation for detecting breast and ovarian cancer
| BRCAaccuTest™ PLUS | ||
|---|---|---|
| Certification | CE-IVD | |
| Target Gene | Breast Cancer/Ovarian cancer HBOC (Hereditary breast and ovarian cancer syndrome) |
|
| Treatment-enhancing methods | Method of Amplicon | |
| Numbers | 12 (6+6) tests (1 tests for DNA control) |
24 tests (1 tests for DNA control) |
| Samples | Blood, FFPE, biopsy tissue | |
| Amount of DNA input | 10-30 ng | |
| Target Gene | BRCA1 / BRCA2 | |
| Target Area | 22.4 kb (all protein coding zones, joins, startup zones selected, UTR, intron regions) | |
| amplicon | 160 (2 pools) | |
| Timing | >5 hrs | |
| Variant | SNV, In, Del, Dup, CNV* | |
| NGS platform & reagent | illumina MiSeq, MiSeq Dx / MiSeq Reagent Nano, Micro kit, v2, 300cycles | |
| Throughput Sample | Germline (11) / Somatic (5) | Germline (23) |
| Analysis Solution | NGeneAnalySys™ (CE) | |
*CNV: Only ROU
Supplier
Ngenebio


The EntroGen NGS Targeted Hotspot Panel is a comprehensive assay that detects clinically relevant mutations in solid tumors using next-generation sequencing, compatible with fresh frozen and FFPE samples. It offers high sensitivity, low DNA input, and the ability to batch up to 12 samples in a single run, making it ideal for labs with limited sample volumes.


SOLIDaccuTest™ is an excellent tool to explorer variants associated with solid tumors using a comprehensive method of next-generation sequencing (NGS). It reflects the latest research trends and is optimized for the medical purpose by selecting essential genes of solid tumors including lung, colon, breast, skin brain, gastric, ovarian cancers, etc.


Model: NextSeq 1000
Manufacturer: Illumina
Origin: Singapore/United States
Launching year: 01/2020


PANA RealTyperTM HPV Kit is a CE marked diagnostic device in accordance with the European Union in vitro Diagnostic Medical Device Directive 98/79/EC.


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– Up to 3 lasers Violet-Blue-Red (V-B-R) and fully activated with 13 colors
– Ability to measure 100 nm particles with violet laser
– Includes 13 band pass filters: 450/45, 525/40 (2), 585/42, 610/20 (2), 660/10 (2), 690/50, 712/25, 780/60 (3)
– For higher throughput applications an optional plate loader module is available
– Smart software in acquisition and analysis CytExpert


Developed with cancer genomics experts in collaboration, oligos ready-to-use, pre-engineered oligos allow researchers to sequence a wide range of genes and single nucleotide polymorphisms (SNPs) in advance. this is related to cancer predisposition


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Model: Nextseq 550
Manufacturer: Illumina/USA
– Is the only sequencing system capable of deploying applications running sequencing and reading microarray biochips
– New generation DNA sequencing system using synthetic sequencing technology: Sequencing by Synthesis – SBS
– The whole process of gene sequencing is conducted on the surface of flow cells, convenient to use and easy to manipulate.


Model: MiSeq
Manufacturer: Illumina/USA
– The MiSeq System combines cluster generation, amplification, sequencing and data analysis on a single system
– The system is most widely used, with next-generation sequencing technology – Sequencing by Synthesis – SBS